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Your next step helps guide the way forward

Enrollment in a clinical trial may give your journey more meaning. And while the path is personal, we know the process of choosing to participate in a clinical trial may be challenging. Learn more about trial opportunities and information to discuss with your care team – so you can explore what may be possible in clinical trials, together.

CURRENT AREAS OF RESEARCH

Insmed is committed to helping people with serious diseases. We’re currently conducting research in the following areas:

Nontuberculous mycobacterial (NTM) lung disease is a rare and serious disorder most commonly caused by Mycobacterium avium complex (MAC). Symptoms may worsen over time and include chronic cough, dyspnea, fatigue, fever, weight loss, and chest pain. In some cases, NTM lung disease can cause severe lung damage.
Chronic Rhinosinusitis (CRS) is inflammation of both the nose and sinuses, including nasal blockage or discharge.
HS is a long-term inflammatory condition that affects areas of the skin with hair follicles and sweat glands, such as the armpits, groin, under the breasts, and buttocks. It causes painful lumps or boils that can rupture and leak pus, often leading to scarring. In more severe cases, tunnels (sinus tracts) can form under the skin, connecting different lesions.
Pulmonary hypertension (PH) is a rare, progressive disease in which the arteries of the lungs become narrowed and stiff. This causes high blood pressure (hypertension) in these arteries.
DMD is a genetic condition that causes progressive muscle weakness. It primarily affects young males and is caused by a mutation in the gene responsible for producing dystrophin, a protein that helps keep muscles strong.

Latest Clinical Trials

Learn more about our current clinical trials. Be sure to talk to your doctor and care team to see if one is right for you.

Nontuberculous Mycobacterial (NTM) Lung Disease
A Study to Evaluate ALIS (Amikacin Liposome Inhalation Suspension) in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex
Trial Status
Active, Not Recruiting
Phase 3
Multiple US locations available
Key Participation Criteria
Current MAC lung infection (untreated)
Adult
Non-smoker
ENCORE
See full study details
Chronic Rhinosinusitis without Nasal Polyps (CRSsNP)
A Study of the Efficacy and Safety of Brensocatib in Participants With Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)
Trial Status
Active, Not Recruiting
Phase 2
Multiple US locations available
Key Participation Criteria
CRS without nasal polyps
Adult
Must not schedule surgery during study at any time
BiRCh
See full study details
Hidradenitis Suppurativa (HS)
A Study of the Efficacy and Safety of Brensocatib in Adults With Moderate to Severe Hidradenitis Suppurativa (HS)
Trial Status
Recruiting
Phase 2b
Multiple US locations available
Key Participation Criteria
Diagnosis of moderate to severe Hidradenitis Suppurativa (HS) for at least 6 months
Adult
HS lesions in at least 2 distinct anatomic areas
CEDAR
See full study details
Duchenne Muscular Dystrophy (DMD)
A Study to Investigate the Safety and Biodistribution of a Single Intrathecal (IT) Injection of INS1201 in Ambulatory Males With Duchenne Muscular Dystrophy (DMD)
Trial Status
Recruiting
Phase 1
Multiple US locations available
Key Participation Criteria
Male, 2-4 years old
Definitive diagnosis of DMD
Ability to walk >10 meters unassisted
ASCEND
See full study details

As research opens new doors to finding ways to diagnose, prevent, treat, or cure disease and disability, clinical trial participation is essential to help us find the answers.

What’s in it for you?

Getting involved in clinical trials helps to advance our understanding of science and diseases. In addition, some patients who join may gain access to:

Better condition understanding
Access to diagnostic tests and education from research team
Enhanced care and monitoring
Frequent and comprehensive checkups with detailed assessments
Thorough screening process
In-depth evaluations that may affect your condition management
Psychological or emotional value
A proactive approach to address overall health
Personalized support
Gained resources including clinicians and care team
Reimbursement for costs
Participation often includes covering study-related expenses

All clinical trials are different and experiences may vary.

It’s also important to keep these factors in mind when deciding whether to apply to a clinical trial:

Convenience of the trial location
Participation could require significant travel to the nearest trial location
Medication may come with side effects
Early testing results may also uncover potential safety concerns
Effectiveness of the drug
Positive treatment results are not guaranteed for trial participants
Experimental treatment may not be given to participants
Those in the “control” group may be given a placebo instead of investigational drug
Significant time commitment
For trial participants as well as caregivers and loved ones that are involved
Impact on daily life
Participation may disrupt daily routines and activities